ATP Science Acetyl L-Carnitine

ATP Science Acetyl-L-Carnitine is an amino acid that has been around for donkey’s years and its efficacy studied immensely. The Acetyl component of this improves the ability to cross the blood brain barrier, improve dopamine and by improving dopamine – it improves other areas such as cognition, learning, attention, memory, desire, pleasure, punishment, reward, motivation, sleep, mood, behaviour, and voluntary movement. It also upregulates the oxidation of fatty acids for the purpose of burning fat and this is done via the Mitochondrial carnitine palmitoyltransferase 1 (CPT1) Pathway. Consuming Acetyl L-Carnitine upregulates the rate limiting fat burning step meaning that you can burn more fat when you exercise.

Acetyl L-Carnitine Benefits the Brain & Body

A large body of scientific evidence points to the positive effects of dietary supplementation of Acetyl L-Carnitine (Acetyl L-Carnitine). Acetyl L-Carnitine is the principal acetyl ester of L-Carnitine (LC), and it plays an essential role in intermediary metabolism, acting as a donor of acetyl groups and facilitating the transfer of fatty acids from cytosol to mitochondria during beta-oxidation. This means it will help you burn fat.

Dietary supplementation of Acetyl L-Carnitine exerts neuroprotective, neurotrophic, anti-depressive and analgesic effects in painful conditions. Acetyl L-Carnitine also has antioxidant and anti-apoptotic activity. Moreover, Acetyl L-Carnitine exhibits positive effects on mitochondrial metabolism, and shows promise in the treatment of aging and neurodegenerative pathologies by slowing the progression of mental deterioration.1

Fat Burning

Fat exhibits a relatively low maximal rate of oxidation in vivo, which begins to decline at around 65% of VO2max when muscle glycogen becomes the major fuel. It is thought that if the rate of fat oxidation during endurance exercise could be augmented, then muscle glycogen depletion could be delayed and endurance improved. Mitochondrial carnitine palmitoyltransferase 1 (CPT1) is thought to be the rate-limiting step in skeletal muscle fat oxidation, but there are several other potential control points that could influence the decline in the rate of fat oxidation during intense endurance exercise including: (1) regulation of lipolysis within adipose tissue; (2) delivery of free fatty acids from adipose tissue to skeletal muscle; (3) transport of fatty acids across the muscle cell membrane and within the cell cytosol; and (4) intramitochondrial enzymatic reactions distal to CPT1.2  Consuming Acetyl L-Carnitine upregulates the rate limiting fat burning step meaning that you can burn more fat when you exercise.

Boosting Dopamine in the Brain

Dopamine in the brain is a good thing for focus and drive when you are training. Boosting the brain’s dopamine before hitting the gym is a goal of lots of pre-workout powders. The great thing is that Acetyl L-Carnitineachieves this goal3, while also have the wonderful ‘side effect’ of promoting fat burning. Dopamine is a hormone that governs much of our brain activity. Dopamine is associated with many neurological functions: cognition, learning, attention, memory, desire, pleasure, punishment, reward, motivation, sleep, mood, behaviour, and voluntary movement. It is no wonder that Acetyl L-Carnitine is a ‘must take’ supplement for the serious trainer.

Studies on the Benefits of Acetyl-L-Carnitine

In mammals, during the aging process, an atrophy of the muscle fibres, an increase in body fat mass, and a decrease in skeletal muscle oxidative capacities occur. Compounds and activities that interact with lipid oxidative metabolism may be useful in limiting damages that occur in aging muscle. In one study, they evaluated the effect of L-carnitine and physical exercise on several parameters related to muscle physiology. They supplemented old rats with L-carnitine for 12 weeks (a) allowed the restoration of L-carnitine level in muscle cells, (b) restored muscle oxidative activity in the muscles, and (c) induced positive changes in body composition: a decrease in abdominal fat mass and an increase in muscle capabilities without any change in food intake.4

Why Should I take ATP Science Acetyl-L-Carnitine?

• ATP Science Acetyl L-Carnitines benefits include:
• Allergen, pesticide, heavy metal and microbial tested for compliance
• Approved material manufacturer that will allow audits of their factory
• HPLC verified guaranteeing fully efficacious material and no contaminants or adulteration
• Vegan friendly
• Gluten GMO & Sugar Free

Mr Supplement Shipping Info

• Mr Supplement ships parcels Australia-wide from Monday to Friday (excluding weekends). 
• Opening hours of store for purchase & pick up orders: Sydney (Seven Hills) & Perth (Wangara) 9 am-4.30 pm Monday to Friday AEST (excluding public holidays). 
• Shipping & Handling Costs – A handling fee of $9.95 for all orders under $150 or FREE Shipping on orders over $150.
• Contact number for other enquiries – 1300 325 797

At Mr Supplement, our promise to you is to have orders dispatched and delivered lightning-fast Australia-wide. Providing your place of delivery has an Australian postcode, rest assured we will get it there as soon as possible.

How do we get it to you so fast? Well, it’s simple really. Firstly we make sure your package is dispatched from one of our two extensive warehouses close to your destination, being either Sydney or Perth. Then we utilise the very fastest transport, which could be via any one of our four (4) dedicated freight companies. Shipments begin being dispatched from both our Sydney & Perth warehouses starting at 10 am daily with the last goods leaving by 5 pm so there are no holding delays.

Secondly, where possible we always use an airfreight service which is why over 85% of our customers receive their orders by the next business day. In short, we don't muck around with shipping. We understand getting your delivery to you fast, without complication & as ordered is the best way of thanking you for trusting us with your supplement business.

Shipping & Handling Costs

A) Our shipping and handling fee is a flat $9.95 Australia-wide or FREE SHIPPING on orders over $150.00. We encourage our customers to reach this amount to take advantage of the FREE DELIVERY offer.

Ordering & Delivery Policy

After choosing to place an order with Mr Supplement we are pleased to advise of the following process which takes place during our business hours (9:00 am-4 pm Monday-Friday EST/EDST).

1. You shall receive an initial confirmation email that your order has been received and is being packed.

2. When goods are dispatched from our warehouse you shall receive a further second email advising your delivery has been successfully shipped.

3. Goods shall be packaged in Mr Supplement branded packaging designed to prevent product damage during transport.

4. Goods ordered prior to 3:15 pm Eastern Australia time (Daylight Saving time when appropriate) shall be dispatched via the fastest method, same business day.

5. Goods are predominately air freighted via one of four transport companies, with delivery extending to all regions of Australia. We utilise multiple transport services as we know this is the only way to ensure the fastest delivery. As a result 85% of our customers receive their goods next working day, with approximately 95% receiving deliveries within 3 working days. Remote or regional areas depending on the exact location may take additional time.

As a tip & for the fastest delivery, we strongly recommend noting a physical street address as opposed to a PO Boxes or Parcel Locker when ordering (PO Box and Parcel Locker deliveries often need to be dispatched via road freight due to Australia Posts freight limitations). In addition, there is unfortunately no option for Express Post service if your order is being sent via Australia Post.

6. Should you wish to track the status of your shipment. Simply log into the Mr Supplement "Locker Room" (your personal member's area) & check your delivery status online.  We store all of your shipping information including consignment notes to make checking your order simple and easy. So please don't hesitate to use this service which is free of charge & there to assist you.

7. For your security, deliveries do require a signature on the receipt. Therefore, delivery should be to an address where someone is available to receive and sign for the goods during business hours. In the event no one is available to receive delivery, a card shall be left advising the package is collectable at the nearest Courier or Australia Post depot.

8. Should you wish for deliveries to be left without signature (i.e. front door etc), this should be noted on your order comments. Mr Supplement is happy to oblige with these requests on small order values, however, we shall hold no responsibility for any lost or missing deliveries should these unfortunate circumstances occur. All large value orders, which are determined by Mr Supplement, for security reasons, may still require a signature regardless of any authority to leave instructions.

9. Mr Supplement, the couriers and transport companies used will try at all times to follow order and delivery instructions wherever possible. However, there may be extenuating circumstances where the order and delivery instructions may be void. If you are unsure whether your order or delivery instructions can be met, please contact MrSupplement, the couriers or the transport companies directly.